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niversity Center for Bioimage Informatics at Carnegie Mellon University

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Jelena Kovacevic and Robert F. Murphy, Directors

Bioimage Informatics draws upon advances in signal processing, optics, probe chemistry, molecular biology and machine learning to provide answers to biological questions from the growing numbers of biological images acquired in digital form. Microscopy is one of the oldest biological methods, and for centuries it has been paired with visual interpretation to learn about biological phenomena. With the advent of sensitive digital cameras and the dramatic increase in computer processing speeds over the past two decades, it has become increasingly common to collect large volumes of biological image data that create a need for sophisticated image processing and analysis. In addition, dramatic advances in machine learning during the same period set the stage for converting imaging from an observational to a computational discipline and allow the direct generation of biological knowledge from images. Hence our slogan: "from image to knowledge."

The Center for Bioimage Informatics (CBI) at Carnegie Mellon was founded as a result of a $9.4 million, five-year, multi-institution Information Technology Research grant from the National Science Foundation. The project is led by B. S. Manjunath at the University of California, Santa Barbara and Robert F. Murphy at Carnegie Mellon. The CBI is directed by Professor Murphy and Professor Jelena Kovacevic. The initial focus of the CBI will be on fluorescence microscope imaging, but the Center is envisaged to grow to encompass work on all biomedical imaging modalities, such as microMRI. Moreover, it is anticipated that the Center will become a focal point of image informatics in the Pittsburgh area.