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Welcome to the Center for Bioimage Informatics!

The Center for Bioimage Informatics (CBI) brings together faculty from engineering, biology and computer science to identify important biological and medical problems in which images are the primary data source, frame a solution to the problem using engineering and computer science principles, collect or obtain relevant images, identify criteria for evaluating success, implement the solution, and evaluate and disseminate the results.

Join us in this exciting endeavor and check out some fun stuff (CBI movie, CBI art)!

Postdoctoral Positions Available

Bioimage and Biosignal Processing Day

The Center for Bioimage Informatics hosted Bioimage and Biosignal Processing Day on February 21st, 2012. The goal of this event was to bring together faculty and researchers from the Pittsburgh area to hear about processing images and signals to solve biological and medical problems. Talks covered computational and statistical methods for the automated analysis of these data, as well as the current and planned infrastrucuture to fasciliate its acquisition, management, and interpretation. The theme this year was "Power in numbers," which includes talks that answer the question "How many neurons are needed to ...?" The plenary speaker was Eberhard E. Fetz, University of Washington.

Seminars - Spring 2012

All CBI seminars take place at 12pm in the CBI Conference Room, Hamerschlag Hall C119, unless otherwise noted. Contact CBI seminar host Ge Yang for more information.

April 11th, 2012

Ervin Sejdic, Department of Electrical and Computer Engineering, University of Pittsburgh

Title: A preliminary study of brain networks associated with swallowing

Abstract: Dysphagia (swallowing impairment) is a common and serious component of many neurological diseases and injuries and frequently involves penetration and/or aspiration (the entry of foreign material into the airway, remaining above, or falling below the vocal cords, respectively). After stroke, dysphagia occurs in 37.78% of patients, with aspiration incidence estimated at 43.54% in those with dysphagia. Stroke patients who aspirate face 11.56 times the risk of developing pneumonia, compared to those without dysphagia. Those who develop pneumonia have a 3-fold increase of death within 30 days. In the broader population of patients with dysphagia of various etiologies, those who aspirate have been shown to be 10 times more likely to develop pneumonia in the ensuing 6 months than those with normal swallowing. These are typical examples where swallowing difficulties can occur. Additionally, aging is known to cause swallowing difficulties as well. Therefore, it is important to understand functional interactions between different brain regions associated of swallowing. In this talk, I will describe our efforts to study brain networks associated with swallowing. In particular, these networks are extracted from functional magnetic resonance imaging (fMRI) recordings obtained from healthy participants.

Latest News

2011

Undergraduate student Leah Yingling has been awarded a CMU Summer Undergraduate Research Fellowship (SURF).
   
Graduate student Mike McCann has been selected to receive the 2011 National Science Foundation (NSF) Graduate Research Fellowship Program (GRFP) Fellowship.
   
Jelena Kovacevic receives 2010 CIT Philip L. Dowd Fellowship Award from the College of Engineering. The Dowd Fellowship is awarded to a faculty member in engineering to recognize educational contributions and to encourage the undertaking of an educational project such as textbook writing, educational technology development, laboratory experience improvement, educational software, or course and curriculum development.

Jelena was recognized for her "profound contributions to BME education through your leadership as Chair of the BME Graduate Affairs Committee, your publication of highly influential textbooks, your efforts in developing new courses to enhance BME graduate programs, and your success as an instructor."
   
Nature Biotechnology recently asked leading computational biology researchers to nominate papers of particular interest published in 2010 that influenced the direction of their research. Work from Bob Murphy's group was chosen as one of four papers highlighted in the resulting article. The featured work, originally described in papers in the Proceedings of the National Academy of Sciences, U.S.A. and Bioinformatics, was the first to provide an automated means of estimating from microscope images how much of a protein (or other marker) is present in different subcellular organelles. The research involved a collaboration with scientists Ghislain Bonamy, Daniel R. Rines, and Sumit K. Chanda from the Genomics Institute of the Novartis Research Foundation in San Diego, and was carried out by graduate students Tao Peng and Luis Pedro Coelho and postdoctoral fellow Estelle Glory-Afshar.
   
Professor Jelena Kovacevic delivered a plenary lecture at IS&T/SPIE Electronic Imaging 2011, held in San Francisco, CA January 23-27, 2011. The meeting gathered 23 technical conferences with researchers covering all aspects of electronic imaging. Professor Kovacevic talked about challenges in biomedical imaging and opportunities for researchers working in signal processing.
   
Graduate student Tao Peng receives Bertucci Graduate Fellowship. Created through the generosity of John and Claire Bertucci, this highly competitive fellowship was established to provide merit fellowships to graduate students pursuing doctoral degrees in the College of Engineering. Congratulations to Tao and his advisor, Robert Murphy!
   

2010

CBI hosted the Bioimage Informatics Conference in September of 2010. See the conference page for more details.

   
 

CBI was well represented at the last BMES conference:

  • Ryan Kellogg , Daniel Delubac , Amina Chebira , Jonathan S. Minden, Jelena Kovacevic, and Stefan F. Zappe, “Imaging technologies for high-throughput Drosophila functional genomics screens”.

  • Chris Highley , Sasha Bakhru , Stefan Zappe, “Hyaluronic acid derivatives or complex coacervation and cellular encapsulation”.

  • Usha Kuppuswamy , Sasha Bakhru , Daniel Delubac , Stefan Zappe, “Perfusion microbioreactor for human adult neural stem cell expansion”.

 
Stefan Zappe, Assistant Professor of Biomedical Engineering and core CBI member, was one of three Carnegie Mellon University researchers to receive the National Science Foundation's Faculty Early Career Development (CAREER) Award, NSF's most prestigious award for junior faculty. Stefan won a $400,000, five-year award to develop MEMS-based fruit fly injection technologies for high-throughput RNAi screens to enable studies of gene function and disease development.
   
Jelena Kovacevic was appointed regular member of the NIH Microscopic Imaging Study Section.